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Particle Accelerators Have a New Target: Cancer
The Millisecond That Could Change Cancer Treatment
FLASH therapy uses a precise burst of ultrahigh-power radiation to kill tumors and spare healthy tissue
Inside a cavernous hall at the Swiss-French border, the air hums with high voltage and possibility. From his perch on the wraparound observation ...
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My Homelab Setup
For the longest time, I’ve procrastinated on finding a good backup and storage solution for my Fujifilm RAW files. My solution up until recently involved manually copying my photos across two external SSD drives. This was quite a hassle and I hadn’t yet figured out a good off-site backup strategy.
A...
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Programming peaked
Programming peaked
by Samir Talwar
Tuesday, 25 November 2025 at 09:00 CET
I remember my first job vividly.
It helps, of course, that I still consider many of the people I worked with friends, and I know some of them even still read this blog. (Hi!)
I also think it might have been the beginning of th...
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We stopped roadmap work for a week and fixed 189 bugs
Discussed on Hacker News, lobste.rs and r/programming
It’s Friday at 4pm. I’ve just closed my 12th bug of the week. My brain is completely fried. And I’m staring at the bug leaderboard, genuinely sad that Monday means going back to regular work. Which is weird because I love regular work. But fixit ...
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The Inference Economy
The Inference Economy
What data center build outs tell us about intelligence costs
Trillion dollar data center buildouts are all the rage. Discussions about powering these data centers, water use, and the wisdom of extremely scaled capex are everywhere — CNBC, SemiAnalysis, and around the dinner tab...
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Fix HDMI-CEC weirdness with a Raspberry Pi and a $7 cable
For years I treated HDMI-CEC like a house spirit: sometimes helpful, mostly temperamental, never fully understood. My living-room stack is straightforward: Samsung TV on ARC (NOT eARC - story for another day), Denon AVR-X1700H hidden in a closet, Apple TV plus a bunch of consoles connected to the re...
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GitHub - pageman/sutskever-30-implementations: Sutskever 30 implementations inspired by https://papercode.vercel.app/
Comprehensive toy implementations of the 30 foundational papers recommended by Ilya Sutskever
Buy the Google Colab Code for this Repo at Gumroad
This repository contains detailed, educational implementations of the papers from Ilya Sutskever's famous reading list - the collection he told John Carmac...
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AI Makes the Easy Part Easier and the Hard Part Harder
Writing on software, systems, and hard-won lessons.
Writing on developer experience, systems thinking, and the mistakes behind both - covering AI workflows, continuous improvement, and the mental models that drive better decisions.
A friend of mine recently attended an open forum panel about how eng...
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How will OpenAI compete? — Benedict Evans
How will OpenAI compete?
“Jakub and Mark set the research direction for the long run. Then after months of work, something incredible emerges and I get a researcher pinging me saying: “I have something pretty cool. How are you going to use it in chat? How are you going to use it for our enterprise p...
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Andrej Karpathy
2023 - 2024
I came back to
OpenAI where I built a new team working on midtraining and synthetic data generation.
2015 - 2017
I was a research scientist and a founding member at
OpenAI.
2011 - 2015
My PhD was focused on convolutional/recurrent neural networks and their applications in computer vision...
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AI Made Writing Code Easier. It Made Engineering Harder.
Yes, writing code is easier than ever.
AI assistants autocomplete your functions. Agents scaffold entire features. You can describe what you want in plain English and watch working code appear in seconds. The barrier to producing code has never been lower.
And yet, the day-to-day life of software en...
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AI is Making Junior Devs Useless - Be a Better Dev
So I got this comment on my last video and it genuinely stopped me in my tracks. It was from @Thiccolo and it reads:
“For someone like you, who likely has years of experience without LLMs, your brain totally understands good code/bad code, good architecture, and just general intuition around code an...
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Mac external displays for designers and developers, part 2
Mac external displays for designers and developers, part 2
Since writing about Mac external displays in 2016, not much has changed. LG, Dell, Samsung, and other display makers have either never catered for the specs many Mac designers and developers want, or they’ve reluctantly produced products tha...
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My 🌶 take on vibe coding for PMs - Daniel D. McKinnon
I shared this internally at Meta in response to a deluge of clout-chasing posts celebrating PMs landing prod diffs. The response was positive and the message generalizes, so here we are on the open www.
PMs shouldn’t waste time landing prod diffs at Meta scale
- If the feature is actually important,...
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Apple Debuts M5 Pro and M5 Max, and Renames Its M-Series CPU Cores
By John Gruber
npx workos: An AI agent that writes auth directly into your codebase.
Apple Newsroom:
Apple today announced M5 Pro and M5 Max, the world’s most advanced chips for pro laptops, powering the new MacBook Pro. The chips are built using a new Apple-designed Fusion Architecture. This innova...
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M5 Pro and M5 Max are surprisingly big departures from older Apple Silicon
As part of today’s MacBook Pro update, Apple has also unveiled the M5 Pro and M5 Max, the newest members of the M5 chip family.
Normally, the Pro and Max chips take the same basic building blocks from the basic chip and just scale them up—more CPU cores, more GPU cores, and more memory bandwidth. Bu...
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A Visual Intro to NumPy and Data Representation
A Visual Intro to NumPy and Data Representation
Discussions:
Hacker News (366 points, 21 comments), Reddit r/MachineLearning (256 points, 18 comments)
Translations: Chinese 1, Chinese 2, Japanese, Korean
The NumPy package is the workhorse of data analysis, machine learning, and scientific computing ...
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NumPy: the absolute basics for beginners#
NumPy: the absolute basics for beginners#
Welcome to the absolute beginner’s guide to NumPy!
NumPy (Numerical Python) is an open source Python library that’s
widely used in science and engineering. The NumPy library contains
multidimensional array data structures, such as the homogeneous, N-dimensio...
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GitHub - mickamy/sql-tap: Watch SQL traffic in real-time with a TUI
Real-time SQL traffic viewer — proxy daemon + TUI / Web client.
sql-tap sits between your application and your database (PostgreSQL, MySQL, or TiDB), capturing every query and displaying it in an interactive terminal UI. Inspect queries, view transactions, and run EXPLAIN — all without changing your...
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Using OpenClaw with Ollama: Building a Local Data Analyst
Course
Modern AI workflows often rely on cloud APIs. But what if you want a system that runs entirely on your machine, keeps data private, and still supports multi-step agent workflows?
In this tutorial, you’ll build a local-first AI execution app where:
- A web interface accepts user requests and f...
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